Laboratory block cancer machine mid boss. The boss with rows of cannons on both sides of the screen. How to effectively kill him? Read this guide.
Guide to Kill Mid Boss
Only worry about defeating the cannons that have health bars under them, the ones that don’t are just there for extra kudos points in case you’re going for a high score. As long as you only focus on those you should be totally fine and the mid boss will be gone within about less than a minute.
Spam Vespa’s weapon, it kills them pretty fast too.
Also you can use Time Slow to give yourself extra time and make dodging their attacks easier. Go after the ones with health bars, but put more priority on just not getting hit. This is pretty easy to do once you have their attacks memorized, since each attack has it’s own simple strategy for not taking a hit, and is choreographed ahead of time.
Specifically target the ones that have the little orbs on them, you should only have to do 5 or 6 waves.