
Resident Evil 2 Remake Laboratory / Lab Puzzle Solution (1st & 2nd Playthrough Solution).
More RE2 Guides:
- 100% Achievement Guide and Puzzle Solutions.
- Lockers, Safe Codes / Combinations and Leon’s Desk.
- Items / Keys Location.
Lab Puzzle Solution
Lab Puzzle Solution in Greenhouse Control Room & Herbicide Cartridge Synthesis in Drug Testing Lab. This guide has all possible solutions for 1st and 2nd playthrough, Leon & Claire.
In first & second playthrough the solutions will be different.
To use the code terminal in the Control Room, think of the blue alien letters as numbers on a keypad or phone. Enter both codes to completely unlock the Drug Testing Lab. Once it’s unlocked, you can access the machine there to make the Herbicide.
Laboratory Codes:
- 3123 & 2067
- 2048 & 5831 (B Scenario)

Herbicide Synthesis:
- A-Scenario: Red, Green, Blue, Red, Green, Blue, Red, Green
- B-Scenario: Blue, Red, Green, Red, Blue, Red, Blue, Green, Blue, Red, Green
Note: Green = Left, Red = Middle, Blue = Right

After this you just need to cool the Herbicide in the Low-Temp Lab in the basement (enter via Ladder in Greenhouse). You’ll notice the door to the Low Temp lab doesn’t open.
Follow the area all the way to the end and you’ll find a Signal Modulator (on 2nd playthrough the signal modulator is where you activate the bridge immediately after getting the general staff keyband). Take the Signal Modulator to the switchbox in the dark hallway before Low Temp Lab.
You can see 3 letters on the switchbox. Examine the Signal Modulator and switch to the 3 letter frequency, then fine tune with the left and right stick until everything lines up.
Now just put the signal modulator in the switch box and the power will turn on. Now you can enter the Low Temp Lab and cool the Herbicide. Afterward, return to the Greenhouse Control Room to disperse the Herbicide.
Be the first to comment